Samantha When I want a dinner that’s impressive enough to serve guests but easy enough to pull off on a weeknight, I reach for my high-protein stuffed chicken breast recipe. This dish takes lean chicken breasts, fills them with a creamy, cheesy spinach mixture, and bakes them until golden, juicy, and flavorful. It’s everything you could want in a healthy chicken dinner—protein-packed, low-carb, and surprisingly simple.
What I love most about stuffed chicken breast recipes is how versatile they are. You can make them with mozzarella and spinach, cream cheese and herbs, or even roasted vegetables for a lighter twist. Not only do they look beautiful sliced open, but they’re also meal-prep friendly, making them a great option for busy weeks.
Chicken breast is one of the leanest protein sources you can cook with. According to Healthline, a single 3.5-ounce (100-gram) chicken breast provides 31 grams of protein with only 165 calories, making it perfect for anyone looking to build muscle, lose weight, or simply eat more balanced meals. By stuffing it with nutrient-rich fillings, you turn a simple cut of chicken into a high-protein dinner recipe that feels indulgent without being heavy.
High-Protein Stuffed Chicken Breast – Juicy Low-Carb Dinner with Spinach, Cheese & Garlic
Ingredients
- 4 large boneless skinless chicken breasts
- 2 cups fresh spinach or 1 cup frozen, thawed & drained
- 1 cup shredded mozzarella or part-skim
- 4 oz cream cheese optional, for creaminess
- 2 cloves garlic minced
- 1 tbsp olive oil
- 1 tsp smoked paprika
- 1 tsp Italian seasoning
- Salt and pepper to taste
- Toothpicks or kitchen twine to secure chicken
Instructions
- Prepare Chicken: Preheat oven to 375°F. Slice a pocket into each chicken breast without cutting all the way through.
- Make Filling: In a skillet, sauté spinach and garlic in olive oil until wilted. Mix with mozzarella and cream cheese.
- Stuff Chicken: Fill each chicken breast with the spinach mixture. Secure with toothpicks.
- Season & Bake: Rub chicken with paprika, Italian seasoning, salt, and pepper. Bake 25–30 minutes, until internal temp reaches 165°F.
- Serve: Rest for 5 minutes, then slice to reveal cheesy filling.
Notes
Secret Tips for the Best High-Protein Stuffed Chicken Breast
1. Pound the chicken evenly: For a juicy stuffed chicken breast, use a meat mallet to pound the chicken to an even thickness. This ensures even cooking and makes it easier to roll or fold around the spinach, cheese, and garlic filling. 2. Dry and season well: Pat the chicken breasts dry before seasoning. A generous coating of salt, pepper, garlic powder, and paprika enhances the flavor and helps create a golden crust when baked or pan-seared. 3. Sauté the spinach and garlic first: Lightly cook the spinach and garlic before stuffing. This removes excess moisture and prevents the cheesy filling from becoming watery inside the chicken breast. 4. Secure the stuffing properly: Use toothpicks or kitchen twine to hold the stuffed chicken together. This keeps the filling of spinach, cheese, and garlic intact while baking for a perfect low-carb dinner. 5. Don’t overcook: Bake until the chicken reaches an internal temperature of 165°F. Overcooking will dry out the meat, but keeping it juicy ensures your high-protein stuffed chicken breast stays tender and flavorful. 6. Rest before slicing: Allow the chicken to rest for 5 minutes after baking. This lets the juices redistribute, making each bite of this protein-packed dinner moist and delicious.Recipe Overview (High-Protein Stuffed Chicken Breast)
- Course: Main Dish, Dinner
- Cuisine: American with Mediterranean Influence
- Skill Level: Beginner-Friendly
- Difficulty Level: Easy
- Prep Time: 15 minutes
- Cook Time: 30 minutes
- Total Time: 45 minutes
- Servings: 4
- Main Ingredients: Chicken breasts, spinach, garlic, mozzarella or cream cheese, seasonings
- Best For: Meal prep, weeknight dinners, high-protein diets, low-carb meals
Nutritional Snapshot
Approximate nutrition per serving (1 stuffed chicken breast):
- Calories: 320
- Protein: 41g
- Fat: 12g
- Saturated Fat: 4g
- Carbohydrates: 4g
- Fiber: 1g
- Sodium: 420mg
- Vitamin A: 45% DV (from spinach)
- Calcium: 15% DV
- Iron: 12% DV
Budget Breakdown
- 4 large chicken breasts: $8.00
- Spinach (2 cups fresh): $2.00
- Garlic (2 cloves): $0.40
- Mozzarella (1 cup shredded): $1.80
- Cream cheese (optional, 4 oz): $1.20
- Olive oil + spices: $0.60
Total Cost: ~$14.00 (about $3.50 per serving)
Behind the Recipe
This high-protein stuffed chicken breast recipe is inspired by my love for meals that feel indulgent but actually support a healthier lifestyle. I used to think of stuffed chicken as a “fancy” dish reserved for restaurants, but once I started experimenting at home, I realized how approachable it really is. All you need is a sharp knife to create a pocket, some flavorful ingredients for stuffing, and the right oven temperature for juicy results.
Stuffed chicken has been enjoyed for centuries, especially in Mediterranean and European kitchens where fresh vegetables, herbs, and cheeses are staples. By adapting that tradition with lighter fillings like spinach and part-skim mozzarella, this dish becomes a healthy stuffed chicken breast recipe that’s ideal for meal prep.
I also love how customizable it is. You can make a baked stuffed chicken breast with mushrooms and onions, a keto stuffed chicken breast with cream cheese, or even a dairy-free version with roasted vegetables. The variations are endless, which is what makes it such a reliable recipe in my weekly rotation.
According to WebMD, chicken isn’t just a protein powerhouse—it also contains selenium, which supports metabolism, and B vitamins, which help maintain energy levels. When you combine that with leafy greens and a touch of healthy fats, you get a dinner that fuels your body while satisfying your taste buds.
For me, this recipe is the perfect example of why I love cooking: it shows that healthy food doesn’t need to be boring, bland, or complicated.
Why You’ll Love This High-Protein Stuffed Chicken Breast Recipe
There’s a reason this high-protein stuffed chicken breast has become one of my go-to dinner recipes—it checks every box for flavor, nutrition, and convenience. By taking lean chicken breasts and stuffing them with spinach, garlic, and mozzarella, you create a dish that’s indulgent yet nutrient-dense. It’s a fantastic way to elevate plain chicken into something restaurant-worthy while still keeping it simple enough for a weeknight.
- Juicy & Flavorful: Thanks to garlic, herbs, and a melty cheese filling, every bite bursts with flavor. Baking locks in the juices, giving you a moist and satisfying chicken dinner.
- Protein-Packed: With over 40 grams of lean protein per serving, this is the ultimate high-protein chicken dinner recipe for meal prep, post-workout meals, or anyone looking to boost their protein intake. According to Cleveland Clinic, protein-rich meals help keep you full longer and support muscle health, making this recipe a win for both flavor and function.
- Meal-Prep Friendly: Cook a batch once, then enjoy multiple portions throughout the week. It reheats beautifully and pairs well with grains, roasted veggies, or salad.
- Versatile: This recipe is a blank canvas. Stuff your chicken with mushrooms, sundried tomatoes, or feta for endless variations.
- Low-Carb & Gluten-Free: Since the filling is made with vegetables and cheese, this dish fits seamlessly into keto, gluten-free, and low-carb diets.
More Recipes You’ll Fall in Love With
- Cozy Classic: Cheese Hamburger Casserole Delight – A cheesy, baked pasta casserole with ground beef that’s hearty, comforting, and family-approved.
- Fresh & Zesty: Lemon Pepper Chickpea Salad – A light, high-protein vegetarian salad tossed with lemon, herbs, and chickpeas for a quick lunch or side.
- Savory Favorite: Creamy Paprika Steak Shells – Tender beef and pasta shells smothered in smoky paprika and garlic cream sauce for the ultimate one-pot meal.
Ingredients You’ll Need
- 4 large boneless, skinless chicken breasts
- 2 cups fresh spinach (or 1 cup frozen, thawed & drained)
- 1 cup shredded mozzarella (or part-skim)
- 4 oz cream cheese (optional, for creaminess)
- 2 cloves garlic, minced
- 1 tbsp olive oil
- 1 tsp smoked paprika
- 1 tsp Italian seasoning
- Salt and pepper, to taste
- Toothpicks or kitchen twine (to secure chicken)
Ingredient Highlights
- Chicken Breasts: Lean, high-protein base that keeps this dish filling.
- Spinach: Adds fiber, vitamins A & K, and iron.
- Mozzarella: Melty cheese that makes the stuffing indulgent yet balanced.
- Garlic: Infuses both the filling and chicken with savory flavor.
- Seasonings: Simple spices elevate the chicken without overpowering it.
Perfect For
This high-protein stuffed chicken breast recipe is one of those rare dishes that works for just about any occasion. It’s hearty, delicious, and packed with lean protein, yet it fits seamlessly into both casual dinners and structured meal plans. By combining juicy chicken breasts with a savory spinach and cheese filling, you get a recipe that’s flexible enough for busy weeknights, meal prep Sundays, or even a dinner party where you want to impress.
- Meal Prep Bowls: Slice your stuffed chicken and layer it with rice, quinoa, or roasted vegetables for a complete high-protein meal prep bowl. It holds up well in the fridge, making it perfect for grab-and-go lunches.
- Weeknight Dinners: Quick to prepare and oven-baked in under 30 minutes, this is one of my favorite easy stuffed chicken breast dinners when I’m short on time but still want something flavorful.
- High-Protein Diets: Each serving delivers over 40 grams of protein, keeping you full and energized. According to EatRight.org, incorporating high-quality protein like chicken breast helps maintain muscle mass while supporting overall health.
- Low-Carb Meals: Naturally low in carbs and gluten-free, this keto stuffed chicken breast fits perfectly into low-carb meal plans without sacrificing comfort.
More Recipes You’ll Fall in Love With
- Protein Boost: Ground Beef Zucchini Skillet – A one-pan, low-carb dinner that’s hearty, flavorful, and meal-prep friendly.
- Comfort on a Plate: Balsamic Baked Chicken Breast with Mozzarella Cheese – Juicy chicken breasts baked with balsamic glaze and melted cheese for an easy but elegant dinner.
- Wholesome Start: Vanilla Cinnamon Buttermilk Pancakes – Fluffy pancakes with a warm vanilla-cinnamon flavor, perfect for a cozy weekend breakfast.
How to Make This High-Protein Stuffed Chicken Breast Recipe
- Prepare Chicken: Preheat oven to 375°F. Slice a pocket into each chicken breast without cutting all the way through.
- Make Filling: In a skillet, sauté spinach and garlic in olive oil until wilted. Mix with mozzarella and cream cheese.
- Stuff Chicken: Fill each chicken breast with the spinach mixture. Secure with toothpicks.
- Season & Bake: Rub chicken with paprika, Italian seasoning, salt, and pepper. Bake 25–30 minutes, until internal temp reaches 165°F.
- Serve: Rest for 5 minutes, then slice to reveal cheesy filling.
Sam’s Pro Tips for Success
- Don’t Overstuff: Too much filling can cause leaks while baking.
- Use a Meat Thermometer: Ensures juicy chicken every time.
- Pan-Sear First: For a golden crust before baking.
- Let It Rest: Slicing immediately can release juices; resting keeps it moist.
Easy Variations You Can Try
One of the reasons I love making high-protein stuffed chicken breast is how easily it adapts to different cuisines and dietary needs. By swapping in a few simple ingredients, you can create endless flavor combinations while still keeping the dish protein-packed, low-carb, and satisfying. These variations prove that you don’t have to stick to just spinach and mozzarella—you can tailor the recipe to whatever you’re craving or what’s already in your kitchen.
- Mediterranean Style: Add sun-dried tomatoes, feta cheese, and olives to the filling. This turns your dish into a Mediterranean stuffed chicken breast recipe that’s salty, tangy, and rich in flavor. It’s perfect for serving with a side of couscous or a Greek salad.
- Caprese Chicken: Stuff the chicken with mozzarella, fresh basil, and tomato slices. Drizzle with balsamic glaze before serving to make a caprese-style stuffed chicken breast that’s as beautiful as it is delicious.
- Mushroom & Onion: Sauté mushrooms with garlic and onions before stuffing. This creates a rich, earthy filling that’s ideal for anyone who loves umami flavors. It’s also a fantastic way to add more vegetables to your healthy stuffed chicken breast dinner.
- Low-Fat Version: Swap cream cheese for Greek yogurt in the filling to cut down on fat while keeping the creamy texture. Greek yogurt is high in protein and probiotics, making this a smart option for anyone following a light high-protein chicken dinner plan. According to Mayo Clinic, Greek yogurt is an excellent substitute for high-fat ingredients and boosts protein content in meals.
These variations prove that once you master the basics of making a stuffed chicken breast, you’ll never run out of ways to keep dinner exciting.
More Recipes You’ll Fall in Love With
- Flavorful Favorite: Shrimp Avocado Mango Bowls – A tropical-inspired high-protein bowl with shrimp, avocado, and mango that’s both refreshing and filling.
- Comforting Classic: Tater Tot Breakfast Bowl with Sausage Gravy – A hearty breakfast bowl loaded with crispy golden tater tots, savory sausage gravy, fluffy scrambled eggs, and melted cheese for the ultimate comfort food start to your day.
- Savory Twist: Donut Grilled Cheese with Bacon Maple – A sweet and savory twist where crispy bacon and gooey melted cheese are sandwiched between glazed donuts, drizzled with maple syrup for the ultimate indulgence.
Storage and Reheat Tips
- Fridge: Store leftovers in airtight containers up to 4 days.
- Reheat: Warm gently in the oven at 300°F or microwave in 30-second bursts.
- Freezer: Freeze stuffed chicken (before or after baking) up to 2 months.
Make It a Meal
Pair this high-protein stuffed chicken breast with these reader favorites:
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Frequently Asked Questions
How much protein is in a stuffed chicken breast?
Each serving has about 40–45 grams of protein, depending on the type of cheese or additional filling used. This makes high-protein stuffed chicken breast an excellent option for muscle-building, weight-loss diets, and meal prep plans.
Is stuffed chicken breast healthy?
Yes! Chicken breast is lean and naturally high in protein. Spinach and garlic add fiber, antioxidants, and essential micronutrients, while cheese provides calcium for strong bones. According to Nutritionix, chicken breast is one of the lowest-calorie, highest-protein meats available, making this dish both filling and nutrient-dense.
Can I meal prep high-protein stuffed chicken breast?
Absolutely. This dish stores well in the fridge for up to 4 days and reheats beautifully in the oven or microwave. Many meal preppers love slicing it and adding it to bowls with rice, quinoa, or roasted vegetables for easy lunches.
Can I make stuffed chicken breast without cheese?
Yes. You can substitute cheese with roasted vegetables, sautéed mushrooms, or even cooked quinoa for a lighter, dairy-free option. This also boosts fiber content while still keeping the recipe high in protein.
What’s the best way to keep stuffed chicken moist?
Bake until just cooked through (165°F internal temperature), then allow the chicken to rest for 5 minutes before slicing. Resting prevents juices from escaping, which keeps your juicy stuffed chicken breast tender and flavorful.
Is this recipe keto-friendly?
Yes, it’s naturally low in carbs and gluten-free, making it an excellent keto stuffed chicken breast dinner idea. Pair it with roasted vegetables or a side salad for a complete keto-friendly meal.
Can I freeze stuffed chicken breast?
Yes. You can freeze it raw (stuffed but unbaked) or fully cooked. If raw, thaw overnight in the fridge before baking. If cooked, reheat in the oven at 325°F until warmed through to maintain texture.
Can I air fry high-protein stuffed chicken breast?
Yes! Place the stuffed chicken in an air fryer at 375°F for 20–22 minutes until golden and fully cooked. Air frying gives it a crispy outside while keeping the inside juicy.
What’s the best filling for high-protein stuffed chicken?
Spinach and mozzarella are classic, but you can use cottage cheese, feta, or even Greek yogurt for a protein boost. Adding vegetables like broccoli or mushrooms not only increases nutrients but also enhances flavor.
How many calories are in a stuffed chicken breast?
On average, a healthy stuffed chicken breast has around 320–350 calories per serving, depending on the filling. This makes it an excellent low-calorie, high-protein dinner option for anyone tracking macros or aiming for weight loss.
Can I make high-protein stuffed chicken breast dairy-free?
Yes, swap out the cheese for dairy-free alternatives or use a mix of roasted vegetables, hummus, or avocado to achieve creaminess without dairy. According to Healthline, avocado is packed with heart-healthy fats and fiber, making it a great addition.
Final Thoughts
At the end of the day, this high-protein stuffed chicken breast recipe proves that eating well can be simple, satisfying, and delicious. With just a few affordable ingredients, you can create a dish that looks restaurant-quality, fuels your body with lean protein, and keeps you excited about healthy eating.
I love making this for my family because it’s a crowd-pleaser. My kids enjoy the melty cheese, I appreciate the nutrient balance, and it reheats beautifully for meal prep. It’s one of those recipes that checks every box—budget-friendly, protein-packed, low-carb, and family-friendly.
So if you’ve been wondering how to make chicken breast more exciting, this is it. Juicy, cheesy, and bursting with flavor, it’s the kind of recipe that will earn a permanent spot in your dinner rotation.
“Juicy, cheesy, and packed with protein—this high-protein stuffed chicken breast proves that healthy meals can be just as comforting as your favorite comfort food.” – Sam
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Juicy chicken breasts filled with creamy spinach and cheese, baked to perfection for a protein-packed dinner or meal prep favorite.
