Samantha If I had to pick just one go-to meal that checks all the boxes—healthy, quick, protein-packed, and full of flavor—this Tzatziki Chicken Pizza would be it. Whether it’s a hectic Monday night or a casual Friday dinner, this dish always delivers with its bold Mediterranean flavor and light, creamy twist. You get juicy grilled chicken, crisp flatbread, and a tangy homemade tzatziki that ties everything together.
The first time I made this recipe, I was craving something like a pizza, but without the greasy heaviness. I had leftover rotisserie chicken and a tub of Greek yogurt in the fridge. A lightbulb moment happened, and within 25 minutes, this pizza was born—warm, fresh, and bursting with garlic, dill, and lemon.
And let’s not forget: this high-protein tzatziki flatbread pizza can hold its own as a balanced meal. It’s low in calories, naturally gluten-free if you want it to be, and flexible enough for meal prep, weeknight dinners, or even light entertaining. If you’re on the hunt for a healthy Mediterranean-inspired pizza recipe, this one should move to the top of your must-try list.
Tzatziki Chicken Pizza – Healthy Mediterranean Flatbread with Greek Yogurt Sauce and Grilled Chicken
Ingredients
For the Flatbread:
- 2 naan or flatbread rounds or gluten-free alternative
- 1 cup cooked chicken breast chopped or shredded
- ½ cup cherry tomatoes halved
- ¼ red onion thinly sliced
- ¼ cup crumbled feta cheese
- Fresh parsley or dill for garnish
For the Tzatziki:
- 1 cup plain Greek yogurt full-fat or 2%
- ½ cucumber grated and drained
- 1 garlic clove minced
- 1 tbsp lemon juice
- 1 tbsp olive oil
- 1 tbsp fresh dill chopped
- Salt & pepper to taste
Instructions
- Prepare the Tzatziki: Combine Greek yogurt, grated and drained cucumber, garlic, lemon juice, olive oil, dill, salt, and pepper. Mix and chill.
- Preheat the Oven: Set your oven to 425°F (220°C) and line a baking sheet with parchment.
- Assemble the Pizza: Place naan on the sheet, spread a generous layer of tzatziki, and top with chicken, tomatoes, red onion, and feta.
- Bake: Bake for 8–10 minutes until edges are crisp and toppings are warmed.
- Garnish and Serve: Top with parsley or dill. Add extra tzatziki if desired.
Notes
Secret Tips for the Best Tzatziki Chicken Pizza
- Use naan or pita for a quick flatbread base: For easy Mediterranean pizza nights, start with store-bought naan or whole wheat pita. It crisps up beautifully and holds the Greek yogurt tzatziki and grilled chicken without getting soggy.
- Marinate the chicken in lemon and herbs: A simple marinade with olive oil, lemon juice, garlic, and oregano gives the grilled chicken authentic Mediterranean flavor and keeps it juicy when baked on the flatbread.
- Strain your Greek yogurt: To keep your tzatziki thick and creamy, strain your Greek yogurt with a cheesecloth or coffee filter for 15–20 minutes before mixing in cucumber and garlic. It prevents a watery sauce on your pizza.
- Use seedless cucumber and grate it finely: This keeps the tzatziki smooth and spreadable while avoiding excess moisture. Squeeze out any liquid before combining with the yogurt.
- Pre-bake the flatbread before topping: Toast the flatbread in the oven for 4–5 minutes before adding toppings. This gives it a crisp base that holds up well under the grilled chicken and creamy tzatziki sauce.
- Add fresh toppings after baking: Save the diced tomato, red onion, cucumber, and feta crumbles for after the pizza comes out of the oven. It adds freshness and balances the creamy and savory layers of your healthy Mediterranean flatbread.
- Drizzle with extra tzatziki or lemon before serving: A finishing touch of cold tzatziki or a squeeze of lemon juice right before serving brings the whole Greek chicken pizza together with a burst of brightness and tang.
Recipe Overview
- Course: Dinner, Lunch
- Cuisine: Mediterranean-Inspired
- Skill Level: Beginner-Friendly
- Difficulty Level: Easy
- Prep Time: 15 minutes
- Cook Time: 10 minutes
- Total Time: 25 minutes
- Servings: 4
- Main Ingredients: Chicken breast, Greek yogurt, cucumber, naan or flatbread
- Best For: Healthy dinners, protein-packed lunches, meal prep, lighter pizza cravings
Nutritional Snapshot
| Nutrient | Amount (per serving) |
|---|---|
| Calories | 370 kcal |
| Protein | 29g |
| Carbohydrates | 28g |
| Fat | 15g |
| Fiber | 3g |
| Sodium | 520mg |
Based on grilled chicken breast, Greek yogurt, naan, and fresh vegetables.
Budget Breakdown
| Ingredient | Estimated Cost |
| Chicken breast (1 cup) | $2.50 |
| Greek yogurt (1 cup) | $1.00 |
| Naan flatbread (2) | $2.00 |
| Veggies & herbs | $1.50 |
| Feta cheese | $1.00 |
| Total: | $8.00 |
| Per Serving: | $2.00 |
Behind the Recipe
Tzatziki Chicken Pizza was born out of my obsession with Greek flavors and my need for simple, nutritious meals that don’t skimp on satisfaction. One night, with a fridge full of meal prep staples—grilled chicken, Greek yogurt, herbs, and a couple of naan rounds—I decided to try something new. Instead of piling it all into a salad bowl or wrap, I turned it into a flatbread pizza.
The result? A Mediterranean-style pizza that’s fresh, savory, creamy, and crisp—all in one bite. It reminds me of open-air cafés in Santorini where the flavors are always bold and the meals always feel clean and complete. This recipe brings that same spirit to your own kitchen.
What I love most is how adaptable it is. You can use leftover rotisserie chicken, skip the cheese, or pile on extra veggies. Plus, it’s a great way to introduce kids to bold flavors like dill, lemon, and cucumber in a way that’s approachable and fun.
Healthline even highlights Greek yogurt as one of the best sources of probiotics and protein, making this dish not just tasty—but truly nourishing too.
Why You’ll Love This
A Fresh, Flavor-Packed Pizza Alternative
If you’re looking to break away from greasy delivery or overly cheesy pies, this Tzatziki Chicken Pizza is your new favorite fix. It delivers the bold, herb-forward taste of a Mediterranean flatbread layered with the creamy tang of homemade tzatziki, juicy lemon-herb grilled chicken, sweet cherry tomatoes, and a crumbling of briny feta. It’s a flavor explosion that feels indulgent without being heavy. Each bite is cooling, savory, and loaded with that fresh-from-the-garden vibe we all crave—especially when you’re aiming for a lighter, balanced meal.
This isn’t just a fun spin on traditional pizza night—it’s a crave-worthy dish that looks gourmet and tastes restaurant-quality, but you can make it in under 30 minutes at home.
High-Protein and Nourishing
What makes this high-protein dinner even more appealing is that it checks all the right boxes nutritionally. With approximately 29g of protein per serving (thanks to lean chicken breast and Greek yogurt), it’s a fantastic option for post-workout meals, low-carb meal plans, or anyone just trying to eat more clean protein without sacrificing flavor. According to WebMD, Greek yogurt is also rich in probiotics and calcium, helping support gut health and bone strength while delivering satiety that lasts.
It’s nourishing, satisfying, and a total game-changer if you want pizza that actually powers you through your day.
Quick and Customizable
One of the biggest reasons I keep this Tzatziki Chicken Pizza in my weekly rotation? It’s quick, flexible, and works with whatever you’ve got in the fridge. Use grilled chicken from a meal prep day, rotisserie chicken from last night, or even leftovers from another dinner. You can make the tzatziki sauce ahead of time and keep it chilled, so all that’s left is assembly and a quick bake.
Want to toss on extra veggies like cucumbers, arugula, or olives? Go for it. Craving spice? Add a drizzle of harissa or chili oil. This recipe is as customizable as it is craveable—making it one of the easiest high-protein Mediterranean meals to pull off, even on a busy night.
Craving More Greek-Inspired Meals?
Don’t miss this one: Greek Yogurt Power Bowl: A Fresh, Protein-Packed Breakfast You Can Build Your Way—another high-protein, clean-eating recipe packed with Mediterranean flair.
Perfect For
Weeknight Dinners
This Tzatziki Chicken Pizza is a lifesaver on busy nights when you want something fast, healthy, and satisfying. It comes together in under 30 minutes, but the Mediterranean-inspired flavor makes it feel like you put in way more effort. The creamy tzatziki sauce paired with lemony grilled chicken and fresh veggies brings a gourmet touch to your usual weeknight dinner rotation.
High-Protein Meal Prep
If you’re all about smart, efficient cooking, this pizza checks the box for high-protein meal prep recipes. Both the tzatziki and grilled chicken can be made in advance and stored in the fridge for several days. Come dinnertime, all you need is a flatbread and a quick bake. It’s a smart and satisfying way to stay on track without feeling like you’re eating the same thing every day.
According to Healthline, meals like this that are rich in lean protein and healthy fats help support muscle maintenance, curb cravings, and improve overall diet quality.
Low-Calorie Pizza Cravings
Sometimes all you want is a slice of pizza—but without the carb overload or greasy finish. This low-calorie pizza alternative delivers the comfort and satisfaction of a slice with a much cleaner nutritional profile. With lean protein, gut-friendly yogurt, and fresh vegetables, it’s the kind of meal you’ll feel great about eating (and even better about enjoying guilt-free).
Light Lunches or Dinners
Serve this Mediterranean flatbread pizza with a Greek side salad, lemony roasted broccoli, or a scoop of quinoa tabbouleh and you’ve got yourself a full-on light but filling lunch or dinner. It’s perfect for when you want something nourishing that still satisfies that craving for something cheesy and warm.
Want Another Fresh and Flavor-Packed Flatbread Idea?
You’ve got to try this next: Garlic Butter Steak Tips with Cheesy Rigatoni—a bold, protein-rich comfort classic that’s surprisingly easy to pull off.
Ingredients You’ll Need
For the Flatbread:
- 2 naan or flatbread rounds (or gluten-free alternative)
- 1 cup cooked chicken breast, chopped or shredded
- 1/2 cup cherry tomatoes, halved
- 1/4 red onion, thinly sliced
- 1/4 cup crumbled feta cheese
- Fresh parsley or dill, for garnish
For the Tzatziki:
- 1 cup plain Greek yogurt (full-fat or 2%)
- 1/2 cucumber, grated and drained
- 1 garlic clove, minced
- 1 tbsp lemon juice
- 1 tbsp olive oil
- 1 tbsp fresh dill, chopped
- Salt & pepper to taste
Ingredient Highlights
Chicken Breast
Lean, high in protein, and versatile. Rotisserie chicken works great too.
Greek Yogurt
Rich in protein and probiotics. According to Healthline, it helps digestion and muscle recovery.
Flatbread
Choose naan or whole wheat flatbread for a soft but sturdy base. Gluten-free versions work just as well.
Cucumber and Dill
These bring the signature cool, crisp flavor to the tzatziki.
Feta Cheese
Salty, tangy, and a perfect finishing touch.
How to Make It
- Prepare the Tzatziki: Combine Greek yogurt, grated and drained cucumber, garlic, lemon juice, olive oil, dill, salt, and pepper. Mix and chill.
- Preheat the Oven: Set your oven to 425°F (220°C) and line a baking sheet with parchment.
- Assemble the Pizza: Place naan on the sheet, spread a generous layer of tzatziki, and top with chicken, tomatoes, red onion, and feta.
- Bake: Bake for 8–10 minutes until edges are crisp and toppings are warmed.
- Garnish and Serve: Top with parsley or dill. Add extra tzatziki if desired.
Pro Tips for Success
- Drain your cucumber well to avoid watery tzatziki.
- Make tzatziki ahead of time for deeper flavor.
- Use an air fryer to reheat leftovers and keep the crust crisp.
- Pre-cook chicken in bulk for faster weeknight prep.
Easy Variations
Tzatziki Chicken Wraps
Turn this Tzatziki Chicken Pizza into a portable, high-protein wrap by rolling everything into a whole wheat tortilla. This variation is perfect for clean-eating lunch ideas or on-the-go dinners. You still get all the creamy, tangy flavor of the tzatziki sauce and juicy grilled chicken—just in wrap form. Add some shredded lettuce or baby spinach for an extra veggie boost.
According to Cleveland Clinic, whole grain wraps can be a healthier choice than traditional sandwich bread, especially when loaded with lean protein and fiber-rich veggies.
Vegetarian Version
For a meatless spin, swap the chicken for roasted chickpeas or grilled zucchini slices. The tzatziki sauce pairs beautifully with plant-based proteins, making this a vegetarian Mediterranean flatbread pizza that’s just as satisfying. This is one of my favorite ways to offer variety without sacrificing flavor or nutrition.
Spicy Greek Pizza
Craving some heat? Drizzle a little sriracha or scatter sliced jalapeños over the toppings before baking. The spice cuts through the creaminess of the tzatziki and balances the richness of the feta. This spicy Greek chicken flatbread pizza version is a bold, flavorful twist that’s still light and protein-packed.
Cauliflower Crust
For a low-carb pizza alternative, swap the flatbread or naan with a cauliflower pizza crust. You’ll still enjoy the crispy texture but with fewer carbs—perfect if you’re following a keto or diabetic-friendly meal plan. Just be sure to choose a crust that doesn’t include added sugars or excess starches.
Hungry for More Clean-Eating Comfort Food?
Check out my Chicken Quinoa Power Bowl—a light, flavor-filled lunch that’s rich in fiber and protein, ideal for meal prep and healthy eating goals.
Storage & Reheat Tips
- Fridge: Store leftovers in an airtight container for 2–3 days.
- Tzatziki: Keep separate in a jar to stay fresh.
- Reheat: Use oven or air fryer to restore crispness.
- Freezer: Not recommended due to fresh veggies and yogurt.
Make It a Meal
Pair this fresh pizza with any of these:
More to enjoy in these recipe collections:
Frequently Asked Questions
What is tzatziki chicken pizza?
Tzatziki chicken pizza is a Mediterranean-style flatbread topped with grilled lemon-herb chicken, creamy homemade tzatziki sauce, and vibrant toppings like cherry tomatoes, cucumber, red onion, and feta. It’s a lighter twist on traditional pizza that brings bold, fresh flavor without greasy ingredients.
Can I use store-bought tzatziki for this recipe?
Yes, you can! Store-bought tzatziki is super convenient, especially for busy nights. That said, I personally prefer to make it from scratch so I can adjust the flavor and texture just how I like it. Plus, homemade versions often skip the preservatives and unnecessary sugar you’ll find in some store brands.
Is tzatziki chicken pizza healthy for weight loss?
It can absolutely support a healthy lifestyle. With high-protein grilled chicken, Greek yogurt instead of heavy cream sauces, and lots of fresh veggies, this pizza is low in calories and refined carbs. The Cleveland Clinic notes that Greek yogurt supports digestion, immunity, and helps with satiety—making it ideal for weight management.
What type of chicken should I use for tzatziki chicken pizza?
I like to use grilled or poached chicken breast for its clean flavor and lean protein content. Leftover rotisserie chicken also works great—just shred or chop it and layer it evenly. You’ll want about one cup per flatbread to keep it balanced.
Can I prep this Mediterranean pizza ahead of time?
Definitely. You can grill the chicken and mix the tzatziki up to three days in advance. When you’re ready to eat, just assemble and bake for a fast weeknight meal. This makes it one of my favorite healthy flatbread recipes for meal prep.
What should I serve with tzatziki chicken pizza?
This pizza shines with light, Mediterranean sides. Try a Greek cucumber-tomato salad, a lemon-dressed quinoa bowl, or a side of roasted vegetables. I also love pairing it with crunchy cucumber ribbons tossed in a light vinaigrette.
Is tzatziki chicken pizza good for meal prep?
Yes—especially if you keep the flatbread separate until ready to bake. Store your grilled chicken, tzatziki, and chopped veggies in separate containers and assemble as needed. It’s one of the best clean-eating pizza recipes for busy weeks.
Can I make this pizza dairy-free?
Totally! Use a plant-based yogurt like coconut or almond milk yogurt for the tzatziki, and skip the cheese or use a dairy-free feta alternative. The rest of the recipe is naturally dairy-free, low in added sugars, and gluten-friendly if you use a GF flatbread.
How much protein does this tzatziki chicken pizza have?
Each serving delivers around 29g of protein, based on the combined amount of grilled chicken and Greek yogurt used. For exact macros, Nutritionix is a great tool to plug in your ingredients and calculate totals.
Can I make this low-carb or keto-friendly?
Yes! Use a cauliflower flatbread or low-carb tortilla as your base. Skip the tomatoes if you’re watching sugar intake and load up on cucumber, spinach, and grilled chicken. This becomes an ideal keto Mediterranean flatbread recipe.
Does tzatziki sauce work as a pizza base?
It absolutely does. The creamy texture and tangy flavor make it a delicious substitute for tomato or white sauce. Plus, the probiotics from the Greek yogurt give it an added nutritional edge that traditional sauces don’t provide.
Is this kid-friendly?
Surprisingly, yes! Most kids love the soft flatbread and creamy tzatziki combo. You can tone down the garlic in the sauce or skip the onions if your little ones are sensitive. It’s a great way to sneak in protein and fresh veggies in a fun pizza format.
Final Thoughts
This Tzatziki Chicken Pizza is more than just a flatbread—it’s my favorite weeknight win. It proves that healthy recipes can be exciting, flavorful, and deeply satisfying. You’ve got your protein, your fiber, your bold herbs, and that irresistible cool-meets-warm contrast that makes each bite craveable.
Whether you serve it to family, friends, or just yourself on a busy Tuesday night, it brings a little Greek-inspired sunshine to your table. If you’ve never had tzatziki on pizza before, now’s your chance to experience the Mediterranean makeover your dinner routine deserves.
Let me know how you top yours—I love seeing your versions!
“Creamy tzatziki, juicy chicken, and fresh herbs on crisp flatbread—this pizza is the ultimate Greek-inspired comfort meal.” – Sam
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Creamy, tangy, protein-packed, and made in under 30 minutes—this Tzatziki Chicken Pizza is a Greek-style flatbread the whole family will crave.
