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Stacked pepperoni pizza rolls on a wooden board showing melted mozzarella cheese, tomato sauce, and crispy golden crust, served with a bowl of marinara dipping sauce.

High Protein Pepperoni Pizza Rolls – Easy Oven-Baked Recipe with Greek Yogurt Dough, Mozzarella & Lean Protein for Meal Prep

Samantha
These High Protein Pepperoni Pizza Rolls are oven-baked, cheesy, and loaded with protein thanks to Greek yogurt dough, mozzarella, and lean pepperoni. Perfect for meal prep, game day snacks, or post-workout fuel, they’re customizable, freezer-friendly, and way healthier than store-bought pizza rolls.
Prep Time 20 minutes
Cook Time 20 minutes
Total Time 40 minutes
Course Appetizer, Main Dish, Snack
Cuisine American, Italian-Inspired
Servings 12 rolls
Calories 120 kcal

Ingredients
  

  • 2 cups self-rising flour or protein flour blend
  • 1 cup plain Greek yogurt
  • ½ cup whey protein powder unflavored or mild flavor
  • 6 oz pepperoni slices
  • 1 cup shredded mozzarella cheese
  • ½ cup marinara sauce plus extra for dipping
  • 1 tsp garlic powder
  • 1 tsp Italian seasoning
  • Olive oil spray for baking

Instructions
 

  • Make the dough: Combine flour, Greek yogurt, protein powder, garlic powder, and Italian seasoning until a dough forms.
  • Roll it out: On a floured surface, roll dough into a rectangle.
  • Layer fillings: Spread marinara, sprinkle mozzarella, and layer pepperoni slices.
  • Roll and slice: Roll dough tightly and cut into 12 pieces.
  • Bake: Arrange rolls on a baking sheet, spray lightly with olive oil, and bake at 375°F for 18–20 minutes until golden.
  • Serve: Enjoy hot with extra marinara for dipping.

Notes

Secret Tips for Perfect High-Protein Pepperoni Pizza Rolls

1. Use Greek Yogurt Dough for Maximum Protein:
Greek yogurt dough isn’t just for convenience—it’s the secret to soft, high-protein pizza rolls that stay chewy on the inside and crisp on the outside. The added protein from the yogurt helps make these rolls filling and satisfying while keeping the texture light and tender.
2. Don’t Overstuff the Filling:
While it’s tempting to load up on mozzarella and turkey pepperoni, overfilling can cause leaks during baking. A balanced amount ensures each bite delivers the perfect ratio of cheesy, saucy goodness and lean protein without the mess.
3. Brush with Olive Oil for Golden Perfection:
Before baking, lightly brush each roll with olive oil or egg wash. This creates that gorgeous golden crust and enhances the overall flavor. It’s especially important when making oven-baked high-protein snacks for meal prep because it keeps them moist even after reheating.
4. Bake on Parchment for Easy Cleanup:
Lining your baking tray with parchment paper prevents sticking and makes post-bake cleanup effortless—ideal for batch cooking or weekly high-protein meal prep sessions.
5. Reheat Like a Pro:
To keep your pepperoni pizza rolls crispy, reheat them in the oven or air fryer instead of the microwave. It restores that just-baked texture while maintaining the gooey mozzarella inside.
6. Add Herbs for Flavor Boost:
A sprinkle of Italian seasoning, oregano, or parsley before baking adds a pizzeria-style aroma and flavor. This small touch elevates your high-protein pizza rolls from simple meal prep to gourmet comfort food.
7. Pair with Protein-Packed Dip:
Serve your pizza rolls with Greek yogurt ranch or marinara mixed with cottage cheese for extra protein. It’s a delicious way to enhance both taste and nutrition.
8. Freeze for Easy Meal Prep:
These rolls freeze beautifully! Let them cool completely, then wrap individually and store in airtight containers. Reheat directly from frozen for a quick, high-protein meal that’s ready anytime.
9. Use Quality Cheese:
Opt for part-skim mozzarella for the perfect melt and extra protein without excessive fat. The cheese helps bind the filling, keeping your oven-baked pizza rolls gooey and irresistible.
10. Experiment with Add-Ins:
Feel free to add chopped veggies like spinach or bell peppers to increase fiber and nutrients. This keeps your high-protein pepperoni pizza rolls more balanced while still hitting that cheesy, savory flavor you crave.
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